MRC Laboratory of Molecular Biology
Neuroscience, Molecular Biology, Neurobiology, Pharmacology, Nematodes
I am a neuroscientist and molecular biologist who is interested in understanding the molecular machinery that allows neurons to communicate with each other.
The basics of neural communication is conserved across species, with neurotransmitters acting as messengers across synapses. My work focusses on the receptors for these neurotransmitters and understanding their diversity and function with the nervous system of the model organism C. elegans. The nematode C. elegans is a powerful model organism, having a small and completely mapped nervous system and genome, allowing us to probe the detailed mechanisms of these receptors within a whole organism. I am particularly interested in ion channel receptors and understanding the way in which their balance at the synapses effects circuits and learning.
To carry out this research I am currently an Investigator Scientist at the MRC Laboratory of Molecular Biology, in the group of Dr William Schafer. My PhD at the university of Cambridge focussed on another group of important neuronal proteins involved in the regulation of hypertension.