European Bioinformatics Institute
biotech, cancer, embryonic development, CRISPR, mathematics
I am a mathematician and computational biologist fascinated by genomics and biotechnology.
Exciting new technologies have enabled investigation of how mutating a specific gene in a single cell affects the cell’s function in a variety of different contexts. I develop algorithms and computational pipelines to analyse data from novel experiments and to optimise the experimental setup, thereby contributing to improved understanding of how genes regulate other genes, of how this varies across cell types and during development, and of the impact of particular mutations in diseases like cancer.
After a degree in mathematics and a career as a teacher, I did a PhD at the MRC Biostatistics Unit in Cambridge specialising in probabilistic and statistical modelling for biological applications. I am now a Sir Henry Wellcome Fellow based at the European Bioinformatics Institute EMBL-EBI. As a computational scientist, I particularly enjoy collaborations with experimentalists in Cambridge and beyond. I am also still involved in teaching, conducting small group teaching for undergraduate mathematics students at the University of Cambridge.